Transplantation of Hematopoietic Stem Cells (Bone Marrow Transplant)
Bone marrow transplantation replaces diseased or injured bone marrow with healthy stem cells. These cells are responsible for producing blood cells. It's needed for conditions like aplastic anemia, leukemia, lymphoma, and immune deficiencies. The procedure involves transplanting healthy stem cells from the patient or a donor. After transplantation, these cells migrate to the bone marrow, restoring blood cell production. Advanced medical technology in India has improved success rates for bone marrow transplants.
Need for Bone Marrow Transplant:
- Bone marrow is essential for proper immune function, and dysfunction can lead to increased susceptibility to infections and diseases.
- Transplantation is necessary for conditions like bone marrow disorders, cancer, or damage from chemotherapy or radiation.
Types of Bone Marrow Transplants:
- Autologous: Uses the patient's own stem cells.
- Allogeneic: Uses stem cells from a donor, categorized into matched sibling, haplo-identical, or unrelated donor transplants.
- Umbilical Cord Blood Transplant: Stem cells harvested from umbilical cord blood of newborns.
Procedure Overview:
- Stem cells are collected from the patient or donor and then administered after conditioning treatment.
- Conditioning treatment involves chemotherapy or radiation to destroy diseased cells.
- Post-transplant, patients undergo monitoring for grafting and blood cell production.
Risk Factors:
- Factors include age, overall health, disease type, and transplant method.
- Complications can include taste impairment, fever, headache, nausea, and blood pressure fluctuations.
Benefits of Bone Marrow Transplantation in India:
- India offers affordability, reliability, and success rates of 60-90% in top hospitals.
- Patients receive holistic care from experienced doctors and advanced medical infrastructure.
- Reduced costs and quality treatment make India an attractive option for bone marrow transplants.
Support and Care:
- Patients receive close monitoring, blood transfusions, immune-suppressing drugs, and medications to manage side effects and infections.